سانچہ:PBB/4193

	Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse)
	Solution structure of Mdm2.
	Available structures: 1rv1, 1t4e, 1t4f, 1ycr, 1z1m, 2axi, 2c6a, 2c6b, 2gv2, 2hdp
	شناختساز
Symbols	MDM2; HDMX; MGC71221; hdm2
بیرونی شناختیں	OMIM: 164785 MGI: 96952 HomoloGene: 1793
وراثی وجودیات
Molecular function:	• ubiquitin-protein ligase activity; • protein binding; • zinc ion binding; • ligase activity; • negative regulator of basal transcription activity; • enzyme binding; • metal ion binding;
Cellular component:	• intracellular; • nucleus; • nucleoplasm; • nucleolus; • cytoplasm;
Biological process:	• regulation of progression through cell cycle; • negative regulation of transcription from RNA polymerase II promoter; • protein complex assembly; • ubiquitin cycle; • traversing start control point of mitotic cell cycle; • negative regulation of cell proliferation; • protein ubiquitination; • regulation of protein catabolic process;
	RNA expression pattern
	More reference expression data
	منتصبات

References

↑ Uhrinova S, Uhrin D, Powers H؛ دیگر (2005)۔ "Structure of free MDM2 N-terminal domain reveals conformational adjustments that accompany p53-binding"۔ J. Mol. Biol.۔ ج 350 شمارہ 3: 587–98۔ DOI:10.1016/j.jmb.2005.05.010۔ PMID:15953616 {{حوالہ رسالہ}}: Explicit use of et al. in: |author= (معاونت)اسلوب حوالہ 1 کا انتظام: متعدد نام: مصنفین کی فہرست (link)