محمد علی کو سانس کی تکلیف کے باعث [[2 جون]]، [[2016ء]] کو ہسپتال میں داخل کروایا گیا۔ ابتدائی طور پر ان کی حالت کو تسلی بخش کرار دیا گیا۔ <ref>{{cite news|last1=Martin|first1=Jill|title=Muhammad Ali hospitalized with respiratory issue|url=http://edition.cnn.com/2016/06/02/us/muhammad-ali-hospitalized-with-respiratory-issue/|accessdate=June 3, 2016|publisher=CNN|date=June 2, 2016|archiveurl=https://web.archive.org/web/20181226052922/https://edition.cnn.com/2016/06/02/us/muhammad-ali-hospitalized-with-respiratory-issue/|archivedate=2018-12-26|url-status=live}}</ref> تاہم اگلے دن علی کی حالت بگڑ گئی۔ <ref>{{cite web | url=http://bigstory.ap.org/article/5466fd876da54f5c8b4b083fcf5cc31e/boxing-great-muhammad-ali-hospital-respiratory-issue | title=Ali remains hospitalized for 'serious' issues | publisher='' AP News '' | date=June 3, 2016 | accessdate=June 3, 2016 | author=Dahlberg, Tim | archive-date=2016-06-03 | archive-url=https://web.archive.org/web/20160603155545/http://www.bigstory.ap.org/article/5466fd876da54f5c8b4b083fcf5cc31e/boxing-great-muhammad-ali-hospital-respiratory-issue | url-status=dead }}</ref><ref>{{cite web | url=http://nypost.com/2016/06/03/muhammad-ali-in-worse-shape-than-earlier-hospital-stays-insiders/?utm_campaign=SocialFlow&utm_source=P6Twitter&utm_medium=SocialFlow | title=Muhammad Ali placed on life support | publisher=''[[New York Post]]'' | date=June 3, 2016 | accessdate=June 3, 2016 | author=Perez, Chris | archiveurl=https://web.archive.org/web/20181226052920/https://nypost.com/2016/06/03/muhammad-ali-in-worse-shape-than-earlier-hospital-stays-insiders/?utm_campaign=SocialFlow&utm_source=P6Twitter&utm_medium=SocialFlow%20 | archivedate=2018-12-26 | url-status=live}}</ref> اس کے بعد ان کی حالت بہتر نہیں ہوئی اور [[3 جون]] کو 74 سال کی عمر میں انہیں مردہ قرار دے دیا گیا۔ <ref>{{Cite web|url=http://www.nbcnews.com/news/sports/muhammad-ali-greatest-all-time-dead-74-n584776|title=Muhammad Ali, 'The Greatest of All Time', Dead at 74|last=Schuppe|first=John|date=June 3, 2016|website=NBC News|publisher=NBC News|access-date=June 3, 2016|archiveurl=https://web.archive.org/web/20181226052925/https://www.nbcnews.com/news/sports/muhammad-ali-greatest-all-time-dead-74-n584776|archivedate=2018-12-26|url-status=live}}</ref><ref>{{Cite web|url=http://www.si.com/mlb/2016/06/03/muhammad-ali-dead-marlins-premature-announcement|title=Marlins prematurely announce death of Muhammad Ali|last=|first=|date=June 3, 2016|website=SI|publisher=SI|access-date=June 3, 2016|archiveurl=https://web.archive.org/web/20181226052917/https://www.si.com/mlb/2016/06/03/muhammad-ali-dead-marlins-premature-announcement|archivedate=2018-12-26|url-status=live}}</ref><ref>[http://abcnews.go.com/US/muhammad-ali-dies-greatest-boxer-dead-74/story?id=18391211 Muhammad Ali Dies: 'The Greatest' Boxer Dead at 74]</ref>